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Cyclone SEQ-WT02 Whole-Genome Nanopore Sequencer

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The Cyclone SEQ-WT02 is an innovative sequencer based on nanopore technology. The device features a unique design with two independent flow cells, providing flexibility in experiment planning and the ability to run tasks with different throughput levels in parallel. Thanks to its...

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The Cyclone SEQ-WT02 is an innovative sequencer based on nanopore technology. The device features a unique design with two independent flow cells, providing flexibility in experiment planning and the ability to run tasks with different throughput levels in parallel. Thanks to its broad coverage, high sequencing speed, and testing flexibility, the Cyclone SEQ-WT02 is ideal for a wide range of research applications, including:
  • microbiome and metagenomic studies,
  • amplicon-based detection of microorganisms,
  • targeted diagnostics of infections and hereditary diseases,
  • whole-transcriptome sequencing,
  • small-genome assemblies.

How It Works

The Cyclone SEQ-WT02 uses nanopore technology, in which DNA libraries bind to motor proteins and are transported to the nanopore protein channels. Under the influence of an electric field, the motor proteins unwind the DNA into a single-stranded form, which passes through the nanopore. Different nucleotides cause changes in the electric current, which are detected by the channel’s sensors. These fluctuations are analyzed in real time using basecalling algorithms, ensuring accurate sequence readout.

Technical Specifications

  • Number of nanopores: 4,096 per flow cell
  • Sequencing speed: 350–420 nt/s
  • Read length: from 100 bp to the megabase level
  • Throughput per flow cell (under laboratory conditions): up to 50 GB
  • Sequencing time: 10 min – 72 h
  • Data acquisition: in real time
  • Single-read accuracy: 97%
  • Consensus accuracy (at 40X coverage): 99.99%
  • Data generation rate: 10 MB/min/flow cell
The Cyclone SEQ-WT02 is the optimal solution for laboratories that require a portable, high-precision, and high-throughput instrument for working with DNA and RNA across a wide range of research applications.  

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